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  • Chemical Biology

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  • Chemical News

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    IXO 1 43 Saurer L4C - 1959 PTT Postbus Schweiz I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… CITROEN DYANE 1 43 NOREV 153717
  • Analytical Chemistry

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    I suppose I deserve this one. Some years ago on the blog, I wrote about my days in grad school having to learn about symmetries and vibrational spectroscopy. Sparingly has that knowledge come in handy since then, but the course is still a vivid memory for me, since that’s the clearest example I had yet… Read More
  • Cancer

  • Drug Assays

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    IXO 1 43 Mercedes O 302-10R - 1972 - bluee white A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

  • Academia (vs. Industry)

    Startup Culture, Starting

    Siku 2919 Sattelkipper Werbemodell Winkler in OVP Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… Brumm BM0130 JAGUAR D TYPE N.9 DNF LM 1955 SPEAR-WALTERS 1 43
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